Program
INDICATION
TARGET ID & VALIDATION
DRUG DISCOVERY
IND ENABLING STUDIES
PHASE I
OTOPROTECTION
Prevention of Cisplatin Ototoxicity
Program
TARGET ID & VALIDATION
DRUG DISCOVERY
IND ENABLING STUDIES
PHASE I
P1b efficacy & safety in cisplatin patients ongoing
GENE THERAPY FOR CONGENITAL DEAFNESS
Otoferlin Deficiency
Program
TARGET ID & VALIDATION
DRUG DISCOVERY
IND ENABLING STUDIES
PHASE I
DB-103*
Undisclosed
Program
TARGET ID & VALIDATION
DRUG DISCOVERY
IND ENABLING STUDIES
PHASE I
DB-103* Undisclosed
DB-104*
Undisclosed
Program
TARGET ID & VALIDATION
DRUG DISCOVERY
IND ENABLING STUDIES
PHASE I
DB-104* Undisclosed
REGENERATIVE MEDICINE: VESTIBULE
Age Related Balance Dysfunction; BVP
Program
TARGET ID & VALIDATION
DRUG DISCOVERY
IND ENABLING STUDIES
PHASE I
Age Related Balance Dysfunction; BVP
Program
TARGET ID & VALIDATION
DRUG DISCOVERY
IND ENABLING STUDIES
PHASE I
Novel Discovery
Age Related Balance Dysfunction
Program
TARGET ID & VALIDATION
DRUG DISCOVERY
IND ENABLING STUDIES
PHASE I
Novel Discovery Novel Discovery Age Related Balance Dysfunction
REGENERATIVE MEDICINE: COCHLEA
Novel Discovery
Sensorineural Hearing Loss
Program
TARGET ID & VALIDATION
DRUG DISCOVERY
IND ENABLING STUDIES
PHASE I
Novel Discovery Sensorineural Hearing Loss

OTOPROTECTION

Target
INDICATION
TARGET ID & VALIDATION
DRUG DISCOVERY
IND ENABLING STUDIES
PHASE I
Prevention of Cisplatin Ototoxicity
Target
TARGET ID & VALIDATION
DRUG DISCOVERY
IND ENABLING STUDIES
PHASE I

GENE THERAPY FOR CONGENITAL DEAFNESS

Target
INDICATION
TARGET ID & VALIDATION
DRUG DISCOVERY
IND ENABLING STUDIES
PHASE I
Otoferlin Deficiency
Target
TARGET ID & VALIDATION
DRUG DISCOVERY
IND ENABLING STUDIES
PHASE I
DB-103*
Undisclosed
Target
TARGET ID & VALIDATION
DRUG DISCOVERY
IND ENABLING STUDIES
PHASE I
DB-103* Undisclosed
DB-104*
Undisclosed
Target
TARGET ID & VALIDATION
DRUG DISCOVERY
IND ENABLING STUDIES
PHASE I
DB-104* Undisclosed

REGENERATIVE MEDICINE: VESTIBULE

Target
INDICATION
TARGET ID & VALIDATION
DRUG DISCOVERY
IND ENABLING STUDIES
PHASE 1
Age Related Balance Dysfunction; BVP
Target
TARGET ID & VALIDATION
DRUG DISCOVERY
IND ENABLING STUDIES
PHASE 1
Age Related Balance Dysfunction; BVP
Target
TARGET ID & VALIDATION
DRUG DISCOVERY
IND ENABLING STUDIES
PHASE 1
Novel Discovery
Age Related Balance Dysfunction
Target
TARGET ID & VALIDATION
DRUG DISCOVERY
IND ENABLING STUDIES
PHASE 1
Novel Discovery Age Related Balance Dysfunction

REGENERATIVE MEDICINE: COCHLEA

Target
INDICATION
TARGET ID & VALIDATION
DRUG DISCOVERY
IND ENABLING STUDIES
PHASE I
Novel Discovery
Sensorineural Hearing Loss
Target
TARGET ID & VALIDATION
DRUG DISCOVERY
IND ENABLING STUDIES
PHASE I
Novel Discovery Sensorineural Hearing Loss

*Currently included in the Decibel Regeneron collaboration.