Program

Target

INDICATION
DISCOVERY
PRECLINICAL
PHASE 1
PHASE 2
PHASE 3
Gene Therapies for Congenital, Monogenic, Hearing Loss
OTOF-Related Hearing Loss
Program

Target

DISCOVERY
PRECLINICAL
PHASE 1
PHASE 2
PHASE 3
GJB2-Related Hearing Loss
Program

Target

DISCOVERY
PRECLINICAL
PHASE 1
PHASE 2
PHASE 3
AAV.104*
Autosomal Recessive Hearing Disorder
Program

Target

DISCOVERY
PRECLINICAL
PHASE 1
PHASE 2
PHASE 3
AAV.104* Autosomal Recessive Hearing Disorder
Gene Therapies for Hair Cell Regeneration
Bilateral Vestibulopathy
Program

Target

DISCOVERY
PRECLINICAL
PHASE 1
PHASE 2
PHASE 3
AAV.201 ATOH1+ Reprogramming Factor
Bilateral Vestibulopathy
Program

Target

DISCOVERY
PRECLINICAL
PHASE 1
PHASE 2
PHASE 3
AAV.201 ATOH1+ Reprogramming Factor Bilateral Vestibulopathy
Cochlear Hair Cell Regeneration
Sensorineural Hearing Loss
Program

Target

DISCOVERY
PRECLINICAL
PHASE 1
PHASE 2
PHASE 3
Cochlear Hair Cell Regeneration Sensorineural Hearing Loss
Otoprotection Therapeutic
Cisplatin-Induced Hearing Loss
Program

Target

DISCOVERY
PRECLINICAL
PHASE 1
PHASE 2
PHASE 3

Gene Therapies for Congenital, Monogenic, Hearing Loss

PROGRAM Target
INDICATION
DISCOVERY
PRECLINICAL
PHASE 1
PHASE 2
PHASE 3
OTOF-Related Hearing Loss
PROGRAM Target
DISCOVERY
PRECLINICAL
PHASE 1
PHASE 2
PHASE 3
GJB2-Related Hearing Loss
PROGRAM Target
DISCOVERY
PRECLINICAL
PHASE 1
PHASE 2
PHASE 3
AAV.104*
Autosomal Recessive Hearing Disorder
PROGRAM Target
DISCOVERY
PRECLINICAL
PHASE 1
PHASE 2
PHASE 3
AAV.104* Autosomal Recessive Hearing Disorder

Gene Therapies for Hair Cell Regeneration

PROGRAM Target
INDICATION
DISCOVERY
PRECLINICAL
PHASE 1
PHASE 2
PHASE 3
Bilateral Vestibulopathy
PROGRAM Target
DISCOVERY
PRECLINICAL
PHASE 1
PHASE 2
PHASE 3
AAV.201 ATOH1+ Reprogramming Factor
Bilateral Vestibulopathy
PROGRAM Target
DISCOVERY
PRECLINICAL
PHASE 1
PHASE 2
PHASE 3
AAV.201 ATOH1+ Reprogramming Factor Bilateral Vestibulopathy
Cochlear Hair Cell Regeneration
Sensorineural Hearing Loss
PROGRAM Target
DISCOVERY
PRECLINICAL
PHASE 1
PHASE 2
PHASE 3
Cochlear Hair Cell Regeneration Sensorineural Hearing Loss

Otoprotection Therapeutic

PROGRAM Target
INDICATION
DISCOVERY
PRECLINICAL
PHASE 1
PHASE 2
PHASE 3
Cisplatin-Induced Hearing Loss
PROGRAM Target
DISCOVERY
PRECLINICAL
PHASE 1
PHASE 2
PHASE 3

*Currently included in the Decibel Regeneron collaboration.